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Welcome to the Stubbendieck Lab at Oklahoma State

Interactions between microbes are facilitated by antibiotics and other secondary metabolites (also called “natural products” or “specialized metabolites”). The Stubbendieck laboratory studies how bacteria synthesize and use these metabolites to mediate competition and cooperation within environmental and host-associated microbiomes.

Currently, we are focused on the microbiomes of the human oral and respiratory tracts, including the mouth, nose, and lower airways in individuals with cystic fibrosis. To characterize how secondary metabolites function in these systems, we take an interdisciplinary approach that integrates traditional microbiology, genomic and metagenomic sequencing, genetics, and natural product chemistry. Our long-term goals are to better understand the ecological and mechanistic functions of secondary metabolites in microbiomes and to identify potential avenues for the development of therapeutics.

Summary of the research framework used in the Stubbendieck Lab

News

Josie Hayes and Sam Ruiz join the Stubbendieck Lab!

Jun 1, 2025 1 min read

Celebrating the End of the Spring Semester and Elixva's Graduation

May 9, 2025

Reed Was Interviewed for the Matters Microbial Podcast

Apr 25, 2025
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© 2025 by Reed Stubbendieck

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